Lamia zaidi biography

  • Moroccan singer who is known for tracks such as "Ken Ya Ma Ken", "Mgharba W Allah Hamdine" and "E-A7BAK".
  • Read Lamia Zaidi's bio and find out more about Lamia Zaidi's songs, albums, and chart history.
  • Moroccan pop singer and songwriter Lamia Zaidi has established herself in the Arabic pop music scene.

    • •

    Biography

    We don't have a wiki rag this creator. Do command know set of scales background substance about that artist?

    Start depiction wiki

    Similar Artists

    1. Salma Rachid

      2,769 listeners

    2. Dounia Batma

      631 listeners

    3. Hoda Saad

      517 listeners

    4. Jannat

      12,067 listeners

    5. Jamila

      4,546 listeners

    6. Ihab Amir

      1,513 listeners

    7. Amal Maher

      3,698 listeners

    8. Aminux

      2,239 listeners

    9. DIZZY DROS

      6,382 listeners

    10. Fayçal Azizi

      3,944 listeners

    11. Latifa Raafat

      997 listeners

    View all like artists

    •

    Abstract

    Maintenance of ATP levels is a critical feature of all cells. Mitochondria are responsible for most ATP synthesis in eukaryotes. We show here that mammalian cells respond to a partial chemical uncoupling of mitochondrial oxidative phosphorylation with a decrease in ATP levels, which recovers over several hours to control levels. This recovery occurs through an increased expression of the transcriptional coactivator peroxisome proliferator-activated receptor-coactivator 1α (PGC-1α) and mitochondrial genes. Cells and animals lacking PGC-1α lose this compensatory mechanism and cannot defend their ATP levels or increase mitochondrial gene expression in response to reduced oxidative phosphorylation. The induction of PGC-1α and its mitochondrial target genes is triggered by a burst of intracellular calcium, which causes an increase in cAMP-response-element-binding protein and transducer of regulated cAMP-response-element-binding proteins actions on the PGC-1α promoter. These data illustrate a fundamental transcriptional cycle that provides homeostatic control of cellular ATP. In light of this compensatory system that limits the toxicity of mild uncoupling, the use of chemical uncoupling of mitochondria as a means of treating obesity should be re-evaluated.

    Keywords: mit

    •

    0003000000010000000000000000000100000000000000000000000100101001
  • lamia zaidi biography